Model info
| Transcription factor | SRF | ||||||||
| Model | SRF_HUMAN.H10DI.A | ||||||||
| Model type | Dinucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Origin | ChIP-Seq | ||||||||
| Model length | 23 | ||||||||
| Quality | A | ||||||||
| Consensus | nbbbbCCWYWYhYRGbvnbnnbn | ||||||||
| wAUC | 0.8017815764530157 | ||||||||
| Best AUC | 0.8864223864831938 | ||||||||
| Benchmark datasets | 10 | ||||||||
| Aligned words | 507 | ||||||||
| TF family | Responders to external signals (SRF/RLM1){5.1.2} | ||||||||
| TF subfamily | SRF{5.1.2.0.1} | ||||||||
| HGNC | 11291 | ||||||||
| EntrezGene | 6722 | ||||||||
| UniProt ID | SRF_HUMAN | ||||||||
| UniProt AC | P11831 | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
|
PCM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | 16.42 | 29.323 | 18.459 | 36.58 | 29.248 | 102.984 | 19.818 | 30.577 | 10.211 | 57.333 | 21.156 | 26.639 | 15.191 | 36.318 | 13.186 | 36.556 |
| 02 | 15.599 | 12.426 | 19.009 | 24.035 | 20.463 | 70.562 | 30.484 | 104.45 | 5.597 | 27.233 | 6.646 | 33.144 | 4.649 | 31.589 | 11.225 | 82.888 |
| 03 | 1.771 | 7.798 | 19.359 | 17.38 | 11.996 | 30.201 | 20.602 | 79.012 | 5.675 | 37.32 | 4.521 | 19.847 | 7.878 | 47.682 | 59.758 | 129.197 |
| 04 | 4.421 | 6.403 | 10.014 | 6.483 | 8.139 | 29.135 | 42.472 | 43.255 | 15.215 | 36.923 | 41.106 | 10.997 | 19.029 | 64.646 | 65.689 | 96.072 |
| 05 | 0.0 | 44.065 | 2.739 | 0.0 | 0.0 | 134.396 | 1.066 | 1.644 | 2.001 | 150.105 | 5.333 | 1.842 | 1.644 | 146.719 | 6.402 | 2.042 |
| 06 | 0.0 | 3.645 | 0.0 | 0.0 | 3.643 | 442.698 | 0.0 | 28.945 | 0.0 | 8.967 | 2.231 | 4.343 | 0.0 | 3.667 | 0.794 | 1.066 |
| 07 | 0.0 | 0.0 | 2.667 | 0.975 | 106.171 | 17.631 | 37.666 | 297.509 | 0.0 | 0.0 | 1.787 | 1.238 | 7.531 | 0.0 | 2.776 | 24.048 |
| 08 | 21.112 | 20.43 | 3.02 | 69.14 | 1.927 | 5.455 | 2.266 | 7.983 | 2.317 | 29.119 | 5.004 | 8.457 | 9.07 | 77.655 | 18.633 | 218.412 |
| 09 | 28.812 | 0.0 | 0.919 | 4.695 | 16.927 | 24.016 | 0.958 | 90.759 | 4.235 | 15.423 | 2.583 | 6.682 | 124.746 | 18.098 | 8.746 | 152.401 |
| 10 | 2.547 | 16.293 | 6.639 | 149.241 | 1.127 | 17.13 | 2.84 | 36.441 | 0.0 | 5.292 | 0.874 | 7.038 | 4.23 | 30.862 | 22.194 | 197.251 |
| 11 | 4.95 | 0.85 | 2.105 | 0.0 | 10.747 | 31.97 | 5.288 | 21.573 | 0.85 | 25.321 | 5.457 | 0.919 | 159.614 | 117.776 | 8.407 | 104.174 |
| 12 | 39.914 | 10.632 | 7.67 | 117.946 | 6.168 | 97.144 | 4.256 | 68.349 | 2.267 | 7.465 | 2.57 | 8.955 | 17.794 | 16.752 | 6.017 | 86.102 |
| 13 | 1.991 | 0.0 | 64.151 | 0.0 | 30.165 | 13.787 | 79.684 | 8.357 | 0.85 | 1.644 | 17.256 | 0.763 | 29.807 | 4.528 | 233.946 | 13.071 |
| 14 | 1.836 | 6.486 | 53.594 | 0.897 | 0.85 | 5.208 | 7.873 | 6.028 | 7.626 | 34.58 | 338.921 | 13.909 | 0.0 | 5.621 | 14.606 | 1.964 |
| 15 | 0.0 | 4.427 | 1.903 | 3.982 | 4.578 | 35.559 | 6.621 | 5.138 | 66.77 | 159.76 | 100.176 | 88.288 | 0.0 | 16.607 | 2.581 | 3.61 |
| 16 | 16.88 | 30.666 | 21.065 | 2.737 | 43.079 | 102.458 | 35.031 | 35.785 | 18.692 | 68.749 | 14.191 | 9.649 | 27.445 | 40.913 | 20.838 | 11.822 |
| 17 | 31.68 | 13.826 | 30.402 | 30.189 | 98.303 | 53.639 | 35.347 | 55.497 | 24.058 | 31.874 | 15.496 | 19.698 | 7.912 | 13.854 | 11.146 | 27.081 |
| 18 | 28.481 | 42.145 | 34.229 | 57.098 | 14.12 | 42.695 | 15.116 | 41.262 | 9.009 | 46.686 | 27.075 | 9.621 | 6.927 | 36.839 | 32.293 | 56.405 |
| 19 | 15.561 | 3.251 | 31.945 | 7.779 | 46.104 | 49.862 | 41.873 | 30.526 | 26.607 | 22.342 | 43.045 | 16.719 | 14.775 | 45.651 | 62.431 | 41.53 |
| 20 | 17.151 | 7.586 | 51.108 | 27.202 | 21.777 | 39.331 | 25.958 | 34.039 | 22.352 | 57.643 | 61.026 | 38.273 | 1.803 | 39.621 | 29.878 | 25.252 |
| 21 | 10.589 | 16.198 | 31.61 | 4.686 | 7.716 | 63.753 | 23.872 | 48.839 | 21.239 | 71.025 | 46.859 | 28.846 | 7.753 | 38.448 | 37.996 | 40.569 |
| 22 | 16.766 | 8.318 | 18.445 | 3.768 | 30.373 | 79.879 | 24.935 | 54.238 | 33.12 | 48.717 | 37.649 | 20.852 | 13.593 | 40.452 | 47.549 | 21.347 |
PWM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | -0.633 | -0.063 | -0.518 | 0.156 | -0.065 | 1.184 | -0.448 | -0.022 | -1.094 | 0.601 | -0.384 | -0.158 | -0.708 | 0.149 | -0.846 | 0.155 |
| 02 | -0.683 | -0.904 | -0.489 | -0.259 | -0.417 | 0.808 | -0.025 | 1.198 | -1.665 | -0.136 | -1.504 | 0.058 | -1.837 | 0.011 | -1.002 | 0.968 |
| 03 | -2.684 | -1.352 | -0.471 | -0.577 | -0.938 | -0.034 | -0.41 | 0.92 | -1.652 | 0.176 | -1.863 | -0.447 | -1.342 | 0.418 | 0.642 | 1.41 |
| 04 | -1.884 | -1.539 | -1.112 | -1.527 | -1.311 | -0.069 | 0.304 | 0.322 | -0.707 | 0.165 | 0.271 | -1.022 | -0.488 | 0.721 | 0.736 | 1.115 |
| 05 | -4.4 | 0.34 | -2.314 | -4.4 | -4.4 | 1.449 | -3.08 | -2.745 | -2.583 | 1.56 | -1.71 | -2.652 | -2.745 | 1.537 | -1.539 | -2.566 |
| 06 | -4.4 | -2.06 | -4.4 | -4.4 | -2.06 | 2.639 | -4.4 | -0.076 | -4.4 | -1.218 | -2.492 | -1.9 | -4.4 | -2.054 | -3.286 | -3.08 |
| 07 | -4.4 | -4.4 | -2.337 | -3.144 | 1.214 | -0.563 | 0.185 | 2.242 | -4.4 | -4.4 | -2.677 | -2.968 | -1.385 | -4.4 | -2.302 | -0.258 |
| 08 | -0.386 | -0.419 | -2.228 | 0.787 | -2.615 | -1.689 | -2.478 | -1.33 | -2.459 | -0.07 | -1.769 | -1.275 | -1.207 | 0.903 | -0.509 | 1.934 |
| 09 | -0.08 | -4.4 | -3.187 | -1.828 | -0.603 | -0.26 | -3.157 | 1.058 | -1.923 | -0.694 | -2.365 | -1.498 | 1.375 | -0.537 | -1.242 | 1.575 |
| 10 | -2.377 | -0.64 | -1.505 | 1.554 | -3.039 | -0.591 | -2.283 | 0.152 | -4.4 | -1.717 | -3.221 | -1.449 | -1.924 | -0.012 | -0.337 | 1.832 |
| 11 | -1.779 | -3.241 | -2.541 | -4.4 | -1.044 | 0.023 | -1.718 | -0.365 | -3.241 | -0.208 | -1.689 | -3.187 | 1.621 | 1.318 | -1.28 | 1.195 |
| 12 | 0.242 | -1.055 | -1.368 | 1.319 | -1.574 | 1.126 | -1.919 | 0.776 | -2.478 | -1.393 | -2.37 | -1.22 | -0.554 | -0.613 | -1.597 | 1.006 |
| 13 | -2.587 | -4.4 | 0.713 | -4.4 | -0.035 | -0.803 | 0.929 | -1.286 | -3.241 | -2.745 | -0.584 | -3.314 | -0.047 | -1.862 | 2.002 | -0.855 |
| 14 | -2.655 | -1.527 | 0.534 | -3.203 | -3.241 | -1.732 | -1.343 | -1.596 | -1.373 | 0.1 | 2.373 | -0.794 | -4.4 | -1.661 | -0.747 | -2.599 |
| 15 | -4.4 | -1.882 | -2.625 | -1.98 | -1.852 | 0.128 | -1.507 | -1.745 | 0.753 | 1.622 | 1.156 | 1.031 | -4.4 | -0.621 | -2.366 | -2.068 |
| 16 | -0.606 | -0.019 | -0.388 | -2.315 | 0.318 | 1.179 | 0.113 | 0.134 | -0.506 | 0.782 | -0.775 | -1.148 | -0.128 | 0.267 | -0.399 | -0.952 |
| 17 | 0.013 | -0.8 | -0.027 | -0.034 | 1.138 | 0.535 | 0.122 | 0.569 | -0.258 | 0.02 | -0.689 | -0.454 | -1.338 | -0.798 | -1.009 | -0.141 |
| 18 | -0.092 | 0.296 | 0.09 | 0.597 | -0.78 | 0.309 | -0.713 | 0.275 | -1.214 | 0.397 | -0.142 | -1.151 | -1.464 | 0.163 | 0.032 | 0.585 |
| 19 | -0.685 | -2.163 | 0.022 | -1.354 | 0.385 | 0.463 | 0.29 | -0.023 | -0.159 | -0.331 | 0.317 | -0.615 | -0.736 | 0.375 | 0.686 | 0.281 |
| 20 | -0.59 | -1.378 | 0.487 | -0.137 | -0.356 | 0.227 | -0.183 | 0.084 | -0.33 | 0.607 | 0.663 | 0.2 | -2.67 | 0.235 | -0.044 | -0.21 |
| 21 | -1.059 | -0.646 | 0.011 | -1.83 | -1.362 | 0.707 | -0.266 | 0.442 | -0.38 | 0.814 | 0.401 | -0.079 | -1.357 | 0.205 | 0.193 | 0.258 |
| 22 | -0.612 | -1.29 | -0.519 | -2.03 | -0.028 | 0.931 | -0.223 | 0.546 | 0.057 | 0.44 | 0.184 | -0.398 | -0.817 | 0.255 | 0.416 | -0.375 |