Model info
| Transcription factor | SMAD2 | ||||||||
| Model | SMAD2_HUMAN.H10DI.C | ||||||||
| Model type | Dinucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Origin | ChIP-Seq | ||||||||
| Model length | 23 | ||||||||
| Quality | C | ||||||||
| Consensus | nhSKCTSdCWSYYnnbnnnnnnn | ||||||||
| wAUC | 0.7577756933337915 | ||||||||
| Best AUC | 0.7807385042269162 | ||||||||
| Benchmark datasets | 3 | ||||||||
| Aligned words | 501 | ||||||||
| TF family | SMAD factors{7.1.1} | ||||||||
| TF subfamily | Regulatory Smads (R-Smad){7.1.1.1} | ||||||||
| HGNC | 6768 | ||||||||
| EntrezGene | 4087 | ||||||||
| UniProt ID | SMAD2_HUMAN | ||||||||
| UniProt AC | Q15796 | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
|
PCM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | 22.767 | 9.023 | 11.568 | 58.687 | 52.856 | 12.896 | 0.0 | 102.738 | 34.132 | 35.617 | 20.467 | 49.166 | 11.253 | 10.127 | 4.317 | 64.386 |
| 02 | 1.98 | 11.91 | 101.075 | 6.045 | 11.803 | 6.644 | 42.409 | 6.806 | 0.0 | 7.239 | 23.85 | 5.263 | 13.723 | 21.172 | 217.095 | 22.987 |
| 03 | 0.0 | 0.0 | 6.095 | 21.41 | 1.818 | 13.415 | 1.147 | 30.585 | 15.353 | 21.155 | 43.261 | 304.659 | 0.97 | 8.381 | 0.988 | 30.762 |
| 04 | 0.97 | 15.343 | 0.0 | 1.828 | 0.0 | 41.104 | 0.0 | 1.847 | 0.0 | 51.492 | 0.0 | 0.0 | 1.914 | 378.766 | 0.0 | 6.736 |
| 05 | 0.0 | 0.0 | 0.0 | 2.884 | 1.945 | 4.351 | 2.046 | 478.363 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 10.411 |
| 06 | 0.0 | 0.0 | 1.945 | 0.0 | 0.0 | 4.351 | 0.0 | 0.0 | 1.131 | 0.0 | 0.915 | 0.0 | 80.48 | 136.461 | 265.498 | 9.22 |
| 07 | 2.964 | 3.605 | 27.619 | 47.422 | 57.947 | 16.102 | 1.809 | 64.954 | 69.734 | 29.07 | 87.359 | 82.195 | 0.982 | 2.059 | 4.366 | 1.813 |
| 08 | 8.022 | 102.659 | 12.714 | 8.232 | 2.264 | 48.572 | 0.0 | 0.0 | 2.044 | 108.289 | 7.122 | 3.699 | 2.188 | 177.149 | 5.381 | 11.665 |
| 09 | 6.227 | 0.0 | 6.266 | 2.025 | 333.84 | 20.374 | 11.061 | 71.395 | 9.085 | 0.0 | 4.194 | 11.937 | 8.97 | 0.97 | 0.951 | 12.705 |
| 10 | 19.699 | 263.572 | 48.834 | 26.016 | 0.891 | 16.438 | 0.0 | 4.014 | 1.185 | 20.243 | 1.045 | 0.0 | 3.637 | 68.904 | 12.795 | 12.726 |
| 11 | 2.75 | 16.037 | 5.718 | 0.907 | 28.045 | 232.908 | 0.0 | 108.204 | 4.399 | 42.439 | 3.689 | 12.146 | 6.033 | 24.251 | 1.259 | 11.214 |
| 12 | 0.988 | 6.988 | 5.994 | 27.257 | 37.682 | 60.785 | 0.0 | 217.169 | 0.0 | 8.795 | 0.0 | 1.871 | 11.014 | 33.805 | 15.108 | 72.544 |
| 13 | 17.237 | 13.712 | 10.5 | 8.236 | 40.659 | 34.189 | 0.0 | 35.525 | 7.759 | 6.638 | 2.631 | 4.074 | 40.31 | 75.822 | 88.953 | 113.756 |
| 14 | 28.657 | 27.381 | 20.645 | 29.281 | 21.648 | 43.556 | 1.147 | 64.009 | 18.986 | 32.049 | 23.964 | 27.086 | 9.956 | 51.387 | 57.667 | 42.58 |
| 15 | 14.035 | 13.74 | 16.903 | 34.571 | 33.226 | 37.466 | 0.999 | 82.683 | 16.021 | 22.191 | 21.65 | 43.561 | 28.638 | 20.304 | 62.33 | 51.684 |
| 16 | 39.547 | 10.134 | 25.124 | 17.114 | 41.155 | 14.624 | 1.989 | 35.933 | 38.779 | 24.861 | 22.336 | 15.906 | 70.06 | 34.505 | 63.732 | 44.201 |
| 17 | 83.272 | 28.717 | 36.529 | 41.022 | 29.907 | 13.592 | 3.802 | 36.824 | 29.472 | 30.059 | 21.192 | 32.458 | 25.428 | 30.479 | 25.989 | 31.257 |
| 18 | 38.286 | 10.45 | 55.382 | 63.962 | 35.382 | 28.34 | 4.901 | 34.223 | 15.23 | 17.103 | 31.204 | 23.975 | 10.841 | 50.475 | 41.524 | 38.721 |
| 19 | 22.894 | 31.431 | 31.599 | 13.816 | 36.651 | 24.743 | 2.666 | 42.309 | 42.343 | 32.9 | 15.895 | 41.874 | 37.169 | 56.028 | 24.749 | 42.934 |
| 20 | 30.681 | 24.694 | 45.504 | 38.177 | 31.891 | 55.998 | 2.161 | 55.051 | 23.356 | 16.821 | 16.439 | 18.293 | 12.05 | 42.098 | 49.176 | 37.61 |
| 21 | 22.045 | 30.538 | 23.319 | 22.076 | 37.125 | 56.311 | 3.918 | 42.257 | 26.188 | 27.697 | 18.63 | 40.765 | 18.334 | 61.828 | 34.66 | 34.309 |
| 22 | 34.007 | 17.511 | 34.305 | 17.868 | 36.619 | 47.767 | 2.867 | 89.121 | 14.868 | 22.96 | 19.24 | 23.46 | 10.873 | 57.45 | 40.244 | 30.84 |
PWM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | -0.312 | -1.212 | -0.973 | 0.624 | 0.521 | -0.868 | -4.4 | 1.182 | 0.087 | 0.129 | -0.417 | 0.449 | -1.0 | -1.102 | -1.906 | 0.717 |
| 02 | -2.592 | -0.945 | 1.165 | -1.593 | -0.954 | -1.504 | 0.302 | -1.481 | -4.4 | -1.423 | -0.266 | -1.722 | -0.807 | -0.384 | 1.928 | -0.303 |
| 03 | -4.4 | -4.4 | -1.585 | -0.373 | -2.663 | -0.829 | -3.026 | -0.021 | -0.698 | -0.384 | 0.322 | 2.266 | -3.148 | -1.283 | -3.135 | -0.016 |
| 04 | -3.148 | -0.699 | -4.4 | -2.659 | -4.4 | 0.271 | -4.4 | -2.65 | -4.4 | 0.495 | -4.4 | -4.4 | -2.621 | 2.484 | -4.4 | -1.491 |
| 05 | -4.4 | -4.4 | -4.4 | -2.269 | -2.607 | -1.899 | -2.565 | 2.717 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -1.075 |
| 06 | -4.4 | -4.4 | -2.607 | -4.4 | -4.4 | -1.899 | -4.4 | -4.4 | -3.036 | -4.4 | -3.189 | -4.4 | 0.938 | 1.465 | 2.129 | -1.192 |
| 07 | -2.245 | -2.07 | -0.122 | 0.413 | 0.612 | -0.652 | -2.667 | 0.725 | 0.796 | -0.071 | 1.02 | 0.959 | -3.139 | -2.559 | -1.895 | -2.665 |
| 08 | -1.325 | 1.181 | -0.882 | -1.3 | -2.479 | 0.437 | -4.4 | -4.4 | -2.565 | 1.234 | -1.438 | -2.047 | -2.508 | 1.725 | -1.702 | -0.965 |
| 09 | -1.565 | -4.4 | -1.559 | -2.573 | 2.357 | -0.421 | -1.016 | 0.819 | -1.206 | -4.4 | -1.932 | -0.943 | -1.218 | -3.148 | -3.162 | -0.882 |
| 10 | -0.454 | 2.121 | 0.442 | -0.181 | -3.208 | -0.631 | -4.4 | -1.972 | -3.001 | -0.428 | -3.094 | -4.4 | -2.062 | 0.784 | -0.875 | -0.881 |
| 11 | -2.311 | -0.656 | -1.645 | -3.195 | -0.107 | 1.998 | -4.4 | 1.233 | -1.888 | 0.303 | -2.049 | -0.926 | -1.595 | -0.25 | -2.955 | -1.003 |
| 12 | -3.135 | -1.456 | -1.601 | -0.135 | 0.185 | 0.659 | -4.4 | 1.928 | -4.4 | -1.237 | -4.4 | -2.639 | -1.021 | 0.078 | -0.714 | 0.835 |
| 13 | -0.585 | -0.808 | -1.067 | -1.3 | 0.26 | 0.089 | -4.4 | 0.127 | -1.357 | -1.505 | -2.349 | -1.959 | 0.252 | 0.879 | 1.038 | 1.283 |
| 14 | -0.085 | -0.13 | -0.408 | -0.064 | -0.362 | 0.329 | -3.026 | 0.711 | -0.49 | 0.025 | -0.262 | -0.141 | -1.118 | 0.493 | 0.607 | 0.306 |
| 15 | -0.786 | -0.806 | -0.604 | 0.1 | 0.061 | 0.179 | -3.127 | 0.965 | -0.656 | -0.337 | -0.362 | 0.329 | -0.086 | -0.425 | 0.684 | 0.498 |
| 16 | 0.233 | -1.101 | -0.215 | -0.592 | 0.272 | -0.745 | -2.588 | 0.138 | 0.213 | -0.226 | -0.331 | -0.664 | 0.801 | 0.098 | 0.706 | 0.343 |
| 17 | 0.972 | -0.083 | 0.154 | 0.269 | -0.043 | -0.817 | -2.022 | 0.162 | -0.058 | -0.038 | -0.383 | 0.037 | -0.203 | -0.025 | -0.182 | 0.0 |
| 18 | 0.201 | -1.071 | 0.567 | 0.71 | 0.123 | -0.096 | -1.789 | 0.09 | -0.706 | -0.593 | -0.001 | -0.261 | -1.036 | 0.475 | 0.281 | 0.212 |
| 19 | -0.307 | 0.006 | 0.011 | -0.801 | 0.158 | -0.23 | -2.338 | 0.3 | 0.301 | 0.051 | -0.664 | 0.29 | 0.172 | 0.578 | -0.23 | 0.314 |
| 20 | -0.018 | -0.232 | 0.372 | 0.198 | 0.02 | 0.578 | -2.519 | 0.561 | -0.287 | -0.609 | -0.631 | -0.527 | -0.934 | 0.295 | 0.449 | 0.183 |
| 21 | -0.344 | -0.023 | -0.289 | -0.342 | 0.17 | 0.583 | -1.994 | 0.299 | -0.174 | -0.119 | -0.509 | 0.263 | -0.525 | 0.676 | 0.102 | 0.092 |
| 22 | 0.084 | -0.57 | 0.092 | -0.55 | 0.157 | 0.42 | -2.274 | 1.04 | -0.729 | -0.304 | -0.477 | -0.283 | -1.033 | 0.603 | 0.25 | -0.013 |