Model info
| Transcription factor | ESR1 | ||||||||
| Model | ESR1_HUMAN.H10DI.A | ||||||||
| Model type | Dinucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Origin | ChIP-Seq | ||||||||
| Model length | 21 | ||||||||
| Quality | A | ||||||||
| Consensus | nnnhhRGGTCAbnbYRhYMbn | ||||||||
| wAUC | 0.8462200055661686 | ||||||||
| Best AUC | 0.9158488163202799 | ||||||||
| Benchmark datasets | 22 | ||||||||
| Aligned words | 278 | ||||||||
| TF family | Steroid hormone receptors (NR3){2.1.1} | ||||||||
| TF subfamily | ER-like receptors (NR3A&B){2.1.1.2} | ||||||||
| HGNC | 3467 | ||||||||
| EntrezGene | 2099 | ||||||||
| UniProt ID | ESR1_HUMAN | ||||||||
| UniProt AC | P03372 | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
|
PCM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | 13.31 | 18.507 | 13.645 | 17.951 | 19.811 | 13.492 | 0.96 | 39.316 | 17.851 | 18.142 | 25.498 | 18.288 | 2.803 | 12.238 | 17.204 | 23.536 |
| 02 | 12.548 | 15.249 | 15.251 | 10.727 | 12.494 | 23.964 | 3.916 | 22.004 | 2.941 | 13.043 | 25.191 | 16.132 | 7.354 | 34.304 | 32.423 | 25.009 |
| 03 | 6.635 | 12.894 | 6.07 | 9.738 | 16.909 | 45.194 | 2.04 | 22.417 | 17.589 | 34.901 | 7.991 | 16.299 | 1.068 | 41.233 | 13.843 | 17.728 |
| 04 | 9.658 | 17.786 | 8.89 | 5.866 | 46.261 | 28.025 | 4.756 | 55.18 | 3.917 | 10.981 | 3.162 | 11.885 | 19.845 | 24.661 | 5.95 | 15.727 |
| 05 | 53.711 | 2.002 | 23.969 | 0.0 | 66.537 | 3.98 | 8.105 | 2.831 | 19.872 | 0.0 | 2.886 | 0.0 | 31.431 | 0.0 | 57.227 | 0.0 |
| 06 | 3.272 | 0.0 | 144.693 | 23.585 | 0.0 | 0.0 | 3.957 | 2.024 | 3.107 | 0.0 | 79.753 | 9.327 | 0.0 | 0.0 | 2.831 | 0.0 |
| 07 | 0.0 | 0.0 | 6.379 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.914 | 225.268 | 5.052 | 0.0 | 0.0 | 33.91 | 1.027 |
| 08 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.914 | 0.926 | 2.857 | 23.04 | 238.734 | 0.0 | 0.0 | 0.0 | 6.079 |
| 09 | 0.0 | 0.926 | 0.0 | 0.0 | 0.0 | 2.857 | 0.0 | 0.0 | 0.0 | 23.04 | 0.0 | 0.0 | 0.0 | 239.663 | 5.136 | 0.928 |
| 10 | 0.0 | 0.0 | 0.0 | 0.0 | 251.613 | 0.0 | 13.916 | 0.958 | 4.103 | 0.0 | 1.033 | 0.0 | 0.0 | 0.0 | 0.928 | 0.0 |
| 11 | 27.485 | 109.99 | 73.063 | 45.178 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 5.828 | 4.028 | 6.021 | 0.0 | 0.0 | 0.958 | 0.0 |
| 12 | 7.854 | 4.823 | 13.839 | 0.968 | 36.842 | 36.014 | 11.057 | 31.906 | 8.834 | 24.052 | 39.021 | 6.14 | 7.125 | 15.071 | 16.232 | 12.771 |
| 13 | 9.668 | 25.122 | 18.038 | 7.828 | 12.699 | 21.486 | 10.623 | 35.153 | 10.67 | 27.153 | 30.878 | 11.448 | 0.0 | 9.821 | 30.167 | 11.796 |
| 14 | 6.891 | 12.342 | 3.028 | 10.776 | 13.581 | 8.111 | 1.052 | 60.839 | 6.233 | 21.414 | 8.013 | 54.047 | 4.912 | 11.12 | 8.047 | 42.146 |
| 15 | 1.934 | 2.033 | 27.649 | 0.0 | 26.398 | 6.243 | 19.334 | 1.012 | 6.295 | 4.917 | 8.927 | 0.0 | 15.841 | 11.1 | 137.882 | 2.987 |
| 16 | 25.916 | 12.788 | 9.771 | 1.993 | 12.232 | 4.93 | 0.0 | 7.129 | 59.116 | 65.179 | 25.698 | 43.798 | 3.024 | 0.975 | 0.0 | 0.0 |
| 17 | 2.004 | 91.366 | 3.903 | 3.014 | 6.95 | 51.308 | 1.919 | 23.697 | 3.801 | 24.646 | 3.098 | 3.924 | 1.062 | 32.89 | 10.199 | 8.77 |
| 18 | 2.113 | 6.875 | 1.906 | 2.922 | 33.516 | 145.429 | 1.996 | 19.268 | 0.985 | 15.237 | 0.0 | 2.897 | 3.997 | 24.577 | 1.0 | 9.831 |
| 19 | 5.977 | 9.318 | 9.0 | 16.316 | 18.161 | 58.888 | 5.924 | 109.145 | 0.0 | 2.895 | 1.0 | 1.008 | 1.052 | 8.422 | 11.864 | 13.581 |
| 20 | 5.724 | 7.23 | 6.029 | 6.207 | 19.169 | 20.989 | 5.018 | 34.347 | 5.863 | 4.826 | 12.186 | 4.915 | 14.054 | 39.991 | 61.439 | 24.565 |
PWM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | -0.241 | 0.081 | -0.217 | 0.051 | 0.148 | -0.228 | -2.585 | 0.825 | 0.046 | 0.062 | 0.397 | 0.07 | -1.707 | -0.323 | 0.01 | 0.318 |
| 02 | -0.299 | -0.108 | -0.108 | -0.451 | -0.303 | 0.335 | -1.405 | 0.251 | -1.664 | -0.261 | 0.385 | -0.053 | -0.814 | 0.69 | 0.634 | 0.378 |
| 03 | -0.912 | -0.272 | -0.996 | -0.544 | -0.007 | 0.963 | -1.984 | 0.27 | 0.031 | 0.707 | -0.734 | -0.043 | -2.506 | 0.872 | -0.203 | 0.039 |
| 04 | -0.552 | 0.042 | -0.632 | -1.028 | 0.986 | 0.49 | -1.225 | 1.161 | -1.404 | -0.428 | -1.599 | -0.351 | 0.15 | 0.364 | -1.015 | -0.078 |
| 05 | 1.135 | -2.0 | 0.336 | -3.904 | 1.347 | -1.39 | -0.721 | -1.698 | 0.151 | -3.904 | -1.681 | -3.904 | 0.603 | -3.904 | 1.198 | -3.904 |
| 06 | -1.568 | -3.904 | 2.121 | 0.32 | -3.904 | -3.904 | -1.395 | -1.991 | -1.615 | -3.904 | 1.528 | -0.586 | -3.904 | -3.904 | -1.698 | -3.904 |
| 07 | -3.904 | -3.904 | -0.949 | -3.904 | -3.904 | -3.904 | -3.904 | -3.904 | -3.904 | -2.621 | 2.563 | -1.169 | -3.904 | -3.904 | 0.678 | -2.535 |
| 08 | -3.904 | -3.904 | -3.904 | -3.904 | -3.904 | -3.904 | -3.904 | -2.621 | -2.611 | -1.69 | 0.297 | 2.621 | -3.904 | -3.904 | -3.904 | -0.995 |
| 09 | -3.904 | -2.611 | -3.904 | -3.904 | -3.904 | -1.69 | -3.904 | -3.904 | -3.904 | 0.297 | -3.904 | -3.904 | -3.904 | 2.625 | -1.153 | -2.61 |
| 10 | -3.904 | -3.904 | -3.904 | -3.904 | 2.674 | -3.904 | -0.198 | -2.587 | -1.362 | -3.904 | -2.531 | -3.904 | -3.904 | -3.904 | -2.61 | -3.904 |
| 11 | 0.471 | 1.848 | 1.441 | 0.963 | -3.904 | -3.904 | -3.904 | -3.904 | -3.904 | -1.034 | -1.379 | -1.004 | -3.904 | -3.904 | -2.587 | -3.904 |
| 12 | -0.751 | -1.212 | -0.203 | -2.579 | 0.761 | 0.738 | -0.421 | 0.618 | -0.638 | 0.339 | 0.817 | -0.985 | -0.844 | -0.12 | -0.047 | -0.281 |
| 13 | -0.551 | 0.382 | 0.056 | -0.754 | -0.287 | 0.228 | -0.46 | 0.714 | -0.456 | 0.459 | 0.586 | -0.388 | -3.904 | -0.536 | 0.563 | -0.359 |
| 14 | -0.876 | -0.315 | -1.638 | -0.446 | -0.221 | -0.72 | -2.518 | 1.258 | -0.971 | 0.225 | -0.732 | 1.141 | -1.195 | -0.416 | -0.728 | 0.894 |
| 15 | -2.029 | -1.987 | 0.477 | -3.904 | 0.431 | -0.97 | 0.124 | -2.546 | -0.962 | -1.194 | -0.628 | -3.904 | -0.071 | -0.418 | 2.073 | -1.65 |
| 16 | 0.413 | -0.28 | -0.541 | -2.004 | -0.323 | -1.192 | -3.904 | -0.843 | 1.23 | 1.327 | 0.404 | 0.932 | -1.64 | -2.573 | -3.904 | -3.904 |
| 17 | -1.999 | 1.663 | -1.408 | -1.642 | -0.868 | 1.089 | -2.036 | 0.324 | -1.432 | 0.363 | -1.618 | -1.403 | -2.511 | 0.648 | -0.5 | -0.645 |
| 18 | -1.954 | -0.878 | -2.042 | -1.67 | 0.667 | 2.126 | -2.003 | 0.121 | -2.566 | -0.109 | -3.904 | -1.678 | -1.386 | 0.36 | -2.555 | -0.535 |
| 19 | -1.011 | -0.587 | -0.62 | -0.042 | 0.063 | 1.226 | -1.019 | 1.84 | -3.904 | -1.678 | -2.555 | -2.549 | -2.518 | -0.684 | -0.353 | -0.221 |
| 20 | -1.052 | -0.83 | -1.003 | -0.975 | 0.116 | 0.205 | -1.175 | 0.691 | -1.029 | -1.212 | -0.327 | -1.194 | -0.188 | 0.842 | 1.268 | 0.36 |